I've been playing around with RapidWeaver, a Mac web authoring application that works similarly to iWeb but produces standards compliant code and allows me to easily change the template from page to page by simply selecting it from the themes pane whilst editing a page.
The more I get involved with it, the more I love it and can honestly say it beats the pants off software like Joomla or Wordpress for my needs, which is mostly 5-10 pages static websites, although I'm using it to develop a 300 page site as well.
Are any of you guys Mac users? Have you tried RapidWeaver? It's shareware, and costs about $79 to buy a license but seems well worth the money. There is a reasonable range of plugins available and a few people have produced third party themes, but the most exciting part of it is integration with the iMedia browser so I don't have to export an image from iPhoto to use it.
I've tested the code it produces and whilst I can't show you a test site yet I can tell you it produces XHTML strict in every page and they validate!
RapidWeaver has some really nice functions like built-in meta tags and titles for each page, and complete control over filenames and permalinks simply because the pages are static HTML pages to begin with.
Adding javascript is a simple thing to do, and can be added in two places, either into the page inspector, or hard coded into the theme, for one of the sites I'm creating I've actually inserted a news ticker into the space normally reserved for a navbar.
If I can find the time to create a new theme for RapidWeaver rather than just butchering one of the existing themes to do what I want then I'll release it here, I was thinking of porting some of the great open source themes to begin with, then work on premium themes later.


